STING1 and infection: Recent studies have reported that the endogenous STING signaling pathway was enhanced during the second stage of SARS-CoV-2 invasion as the infection brings about an interaction between cytosolic self-destructed DNA that activates the STING signaling pathway, consequently leading to severe inflammatory responses in patients [139,140] and revealing that the belated administration of STING agonists during the late infection stage of SARS-CoV-2 might lead to adverse prognosis.