In addition, genetic investigation of the relatives of patients with Gaucher disease allows the identification of pauci- or pre-symptomatic subjects, who, in this way, can start specific therapy as early as possible before organ involvement becomes irreversible, and subjects carrying mutations in the GBA1 gene, a condition to date considered a risk factor for Parkinson’s disease [19,20]. This evidence concerns the gene GBA1 and Parkinson disease.