In myelin oligodendrocyte glycoprotein peptide 35–55 (MOG35–55)-induced multiple sclerosis (MS), arthritogenic K/BxN serum-induced rheumatoid arthritis (RA), and monosodium iodoacetate (MIA)-induced OA models of female and male mice, IL-1β-producing myeloid cells were found to infiltrate around IL-1 receptor-expressing nociceptors in DRG. This evidence concerns the gene IL1B and rheumatoid arthritis.