F2 and hepatocellular carcinoma: Table 1 lists the Spearman’s correlation (ρ) and p-values. Moderate significant correlations (ranging from ρ 0.53 to 0.45) were identified for transaminases and transferase in the following order: ALT > AST > GGT. The risk factor for HCC development, age at the time of diagnosis, presented a significant association with AFP (ρ 0.49, p-value < 0.0001). Other liver function biomarkers, such as prothrombin time, total bilirubin, and alkaline phosphatase, were significantly associated with AFP but weaker (ranging from ρ 0.29 to 0.208, p-value < 0.001).