We notably found that the protein levels of Lox and Loxl3 were elevated at week 1 and 1 month in isolated cardiac fibroblasts treated with TGF-β from MI mice, and these proteins centrally involve crosslinking and stabilising collagen and elastin fibres, including cardiac remodelling [30,31]. This evidence concerns the gene TGFB1 and myocardial infarction.