This study aimed to investigate the effect of MI on cardiac fibroblasts by comprehensively characterising resulting changes in the proteome of these cells from the different time points post-infarct induction (inflammatory phase, proliferative phase, and remodelling/maturation phase) along with examining the changes in response to pro-fibrotic activation by TGF-β. The gene discussed is TGFB1; the disease is myocardial infarction.