In contrast to diabetic rats, the diabetes + PACAP group had a more sensitive response in all amplitudes, like the a-wave (79.9 ± 13.59 μV (diabetes) vs. 174.23 ± 9.12 μV (diabetes + PACAP)), b-wave (200.08 ± 17.55 μV (diabetes) vs. 476.05 ± 26.69 μV (diabetes + PACAP)), and oscillatory potential waves (72.99 ± 4.89 μV (diabetes) vs. 149.75 ± 9.64 μV (diabetes + PACAP)) (Figure 2B–D). This evidence concerns the gene ADCYAP1 and diabetes mellitus.