ADCYAP1 and diabetes mellitus: In the intraperitoneal glucose tolerance test, the 2 h glucose value of rats with diabetes (diabetes group and diabetes + PACAP group) was three times higher than in control rats (24.12 ± 2.2 mmol/L (diabetes) vs. 7.48 ± 0.31 mmol/L (control); 19.55 ± 2.32 mmol/L diabetes + PACAP) vs. 6.58 ± 0.34 mmol/L (control + PACAP)) (Figure 1A).