ADCYAP1 and diabetes mellitus: In contrast to the diabetes group, the percentage of vessel density from the diabetes + PACAP group presented higher in the peripheral area (36.08 ± 1.83% (diabetes) vs. 43.13 ± 1.55% (diabetes + PACAP)) and the edge region (27.43 ± 2.62% (diabetes) vs. 33.96 ± 1.12% (diabetes + PACAP)) (Figure 6A,B).