TNF and type 2 diabetes mellitus: The third primary objective of the study was to assess the diagnostic accuracy of PTX3, hs-CRP, TNF-α, IL-6, NLR, MLR, PLR, AISI, SII, MCVL, and IIC as individual early predictive indicators and to determine the inflammatory status in patients with and without T2DM, by employing a receiver operating characteristic (ROC) curve analysis.