Numerous studies conducted over recent decades have established a positive correlation between diabetes and suboptimal levels of inflammatory markers and mediators [C-reactive protein (CRP), interleukin-1beta (IL-1b), IL-6, tumor necrosis factor-alpha (TNF-α), leptin, adiponectin, and adipocytokine] [5,6,7,8,9,10,11,12,13]. Here, TNF is linked to diabetes mellitus.