MYOD1 and muscle atrophy: However, the mRNA expression of MyoD and IGF-I, reduced in the muscle atrophy control group (G2), was significantly elevated in both the 50 mg/kg and 100 mg/kg AJHW treatment groups (G4, G5), while myogenin mRNA expression, also reduced in the muscle atrophy control group (G2), substantially increased in all of the treatment groups (G4, G5, G6).