WT1 and familial nephrotic syndrome: According to Eujin Park, WT1 defect was the most frequently detected pathogenic variant in a study of congenital nephrotic syndrome (CNS) [30], where a total of 57 genes were analyzed, while Zhu et al., in a large cohort study of 283 patients from the Chinese population, identified WT1 gene pathogenic variants as the most common cause of SRNS [31], with 26 genes being examined.