IL6 and injury: Some studies have shown that the polysaccharides from medicinal plants such as Polygonatum cyrtonema enhance SOD and Nrf2 expression in LPS-induced acute lung injury models [76], while honey-derived polysaccharides have been linked to reduced IL-1β, IL-6, and TNF-α levels, alongside increases in IL-10 and Nrf2 activation [77].