Interestingly, median [IQR] urine concentrations of EVs derived from T-cells (CD3+) and tubular cells (aquaporin-1+) were higher in KT recipients with TCMR than in KT recipients with ABMR, AD, or renal recovery (respectively, 365 [185–767], 244 [75–310], 241 [113–402], and 354 [235–855]/μL; p = 0.06; and 1751 [357–2051], 681 [283–1016], 509 [218–919], and 827 [355–1236]/μL; p = 0.15), although these differences were not statistically significant. This evidence concerns the gene AQP1 and Alzheimer disease.