Among the monitored laboratory parameters, patients with acute cholecystitis showed significantly higher levels of leukocytes (11,312 vs. 8695 n/μL; p = 0.002), alkaline phosphatase (134.0 vs. 100.81 U/L; p = 0.006), CA 19-9 (187.01 vs. 24.32 ng/mL; p = 0.001), CEA (9.54 vs. 2.36 ng/mL; p = 0.001), AFP (8.03 vs. 4.64 ng/mL; p = 0.001), and CA-125 (198.93 vs. 23.59 ng/mL; p = 0.001), while amylase values were significantly lower (53.24 vs. 242.08 U/L; p = 0.015). The gene discussed is CEACAM5; the disease is Cholecystitis, Acute.