This bacterial strain is considered as a major OM-related EMT inducer in OSCC, as it has been demonstrated that it can promote ERK1/2-Ets1-p38- and NF-kB-mediated MMP-9 expression, as well as EMT induction via the JAK/STAT pathway and neutrophil CXCL2/CXCR2-dependent chemotaxis [178,179]. This evidence concerns the gene MMP9 and ocular melanoma.