A case study suggests that FMT may serve as a potential therapeutic approach for severe psoriasis, as a patient receiving two FMT treatments showed significant improvements in PASI, BSA, and DLQI scores, as well as intestinal symptoms, with a marked reduction in TNF-α levels and no reported adverse effects; however, further clinical trials are required to establish its efficacy [369]. The gene discussed is TNF; the disease is psoriasis.