Among these, 50 genes are predominantly associated with all types of AD, including APP, PSEN1, PSEN2, APOE, MAPT, IDE, IGF2, GSK3B, HFE, ABCA7, IL1B, BACE1, APOC1, SOD2, CST3, IGF1R, ATP5F1A, BIN1, ABCA7, ACE, PLAU, and TREM2 [150]. The gene discussed is ABCA7; the disease is Alzheimer disease.