However, MLB cells isolated from TNBS-induced colitis rats significantly promoted the differentiation of intestinal CD4+ T cells from colitis rats into Th1 cells (Figure 7A) while inhibiting their differentiation into Th2 cells (Figure 7B), consistent with the findings observed in the adoptive transfer experiments of TNBS-induced MLB cells into colitis rats (Figure 6C,E). Here, CD4 is linked to colitis.