In the pathogenesis of epilepsy, despite the experts’ disagreement on the primary pathological process (seizures or damage to the BBB), the main neuroinflammatory process is considered to be the mobilization of the cytokines IL-1β, IL-6, and TNF-α in response to pathological changes in the CNS caused by traumatic brain injury (TBI), brain tumors, stroke, drug exposure, etc. [145,146]. Here, TNF is linked to Stroke.