Specially, five SNPs (rs17857295, rs4244165, rs6084497, rs16989000, and rs4612666) were associated with HIV-1 infection, three SNPs (rs2066804, rs1143623, and rs1467199) were associated with CD4 T+ cell counts in patients with AIDS, and three SNPs (rs867335, rs10754558, and rs1131454) were found to be related to the clinical staging of AIDS. This evidence concerns the gene CD4 and AIDS.