GH1 and X-linked hypophosphatemia: Several studies explored the efficacy of recombinant human growth hormone (rhGH) on height in XLH children and showed that rhGH was beneficial for height improvement in affected children with XLH (43, 44, 45, 46), especially in those combined with growth hormone deficiency and pre-pubertal children (28, 44), but the aggravated bone deformities and abnormal body disproportion should be concerned (13, 46).