Our data identify a broad trend toward an increase in PD-L1 expression on all immune cells (CD45+) in the AB12 tumor microenvironment and a significant increase (P = 0.014) in PD-L1–positive tumor and stromal cells (CD45−) at 1 day after TI versus TC (Fig. 3A and B). The gene discussed is PTPRC; the disease is neoplasm.