CD274 and neoplasm: At day 5 after TI, no change was detected in the percentage of tumor-associated Ly6G+ or Ly6G− cells or their PD-L1 levels (Fig. 3E and F), although there is a slightly higher proportion of Ly6C+ M-MDSCs after TI compared with TC (22% in TI vs. 16% in TC; P = 0.041; Supplementary Fig. S4A).