Additionally, the use of a nephelometric assay for the determination of Lp(a) did not allow for evaluating the different apoprotein(a) [apo(a)] isoforms; however, there are data indicating that the Lp(a) serum level is the main CAD risk indicator, while isoform size does not significantly contribute to risk [22]. The gene discussed is AOPEP; the disease is coronary artery disorder.