PECAM1 and Timothy syndrome: Gating on the CD4+CD3+ population, the percentage of naïve cells (CD45RA+CD27+), was increased in the PIMS-TS patients compared to healthy children (Fig. 2C), but we found no differences in mean proportions of CD4 RTE (CD45RA+CD31+) or naïve (CD45RA+CD27+) cells within the CD8 population (Fig. 2D-E).