Several studies used ARPE‐19 cells to represent RPE cells for models of eye diseases because the differentiation of ARPE‐19 cells can express RPE‐specific markers, including RPE65 and CRALBP, that achieve phenotypic characteristics closer to those of native RPE cells, especially when studying retinal pathophysiology and treatment effects (Dunn et al. 1996; Samuel et al. 2017). Here, RLBP1 is linked to eye disorder.