AAV vectors of OA may trigger excessive inflammatory responses according to Galletta et al. This study mined alert signals for inflammatory indicators (e.g., C-reactive protein increased, white blood cell count increased, monocyte count increased, platelet count increased) and alert signals for infections (e.g.,pneumonia, rhinovirus infection, nasopharyngitis, respiratory syncytial virus infection, pneumonia aspiration, upper respiratory tract infection, respiratory tract infection, viral infection, and lower respiratory tract infection), which were not mentioned on the label. The gene discussed is CRP; the disease is infection.