ESR1 and atherosclerosis: Interrogation of Stockholm-Tartu Atherosclerosis Reverse Networks Engineering Task,21 which includes RNA sequencing of 9 tissues from 850 subjects, 600 with coronary artery disease (CAD; 70% male) and 250 without CAD (55% males), indicates that skeletal muscle ESR1 expression is inversely correlated with CAD risk (−0.14475, p value = 0.00085399).