In mesenchymal gastric cancer cells (GCs), Elongated long-chain fatty acid protein 5 (ELOVL5) and fatty acid desaturase 1 (FADS1) promote unsaturated fatty acid synthesis, but in enteric GC, these genes are suppressed by DNA methylation, rendering the cells resistant to ferroptosis [112]. The gene discussed is FADS1; the disease is gastric cancer.