Among the identified genes, we selected Rora (Figure 6D) and Ccr6 (Figure 6E) to examine more closely for evidence of epigenomic activation in AD-like disease, given the role of these genes in ILC2 expansion (Wong et al., 2012; Halim et al., 2012) and homing to sites of inflammation (Ricardo-Gonzalez et al., 2018; Kobayashi et al., 2019), respectively. This evidence concerns the gene CCR6 and Alzheimer disease.