Additionally, m6A levels in colorectal cancer Te‐EVs correlated with TNF‐α and IL‐6 levels in the paired cancer tissue, suggesting that while colorectal cancer EVs do not affect the number of tumour‐infiltrating macrophages, they may contribute to recurrence by increasing the production of TNF‐α and IL‐6 production in macrophages. Here, TNF is linked to colorectal cancer.