The stimulation of PMCA activity observed in astrocyte cell lines after being treated with Aβ or tau differs from the downregulation of PMCA activity (but not SERCA) found in our previous studies with SH‐SY5Y human neuroblastoma cells treated with Aβ [51] or with tau [50, 51], and it was supported in this work by treating this cell line and other neuronal cell lines, such as HT‐22 and N2a, with cytokines, Aβ or tau (Table S1). Here, MAPT is linked to neuroblastoma.