Other works have reported that Aβ peptide induces an inflammatory response in primary astrocyte cultures from rats [59], and that reactive (GFAP‐positive) astrocytes, with high Aβ content, are often accumulated in AD‐affected brains [4, 5, 56, 60, 61], because they may reduce the capacity of astrocytes to degrade the peptide, and then, this can be a central process in the Aβ toxicity. This evidence concerns the gene GFAP and Alzheimer disease.