ALK and non-small cell lung carcinoma: to harness CRBN to degrade anaplastic lymphoma kinase (ALK), an important target in non‐small cell lung cancer (NSCLC).[59] Au nanoclusters (2‐3 nm) were used to degrade HER2 through a PROTAC‐based approach also harnessing CRBN.[60] Au nanoclusters have advantages over Au NPs as they are much smaller (2–4 nm) and consequently provide a much higher surface‐to‐volume ratio.