AURKA and hepatocellular carcinoma: AURKA may promotes tumorigenesis via cell proliferation, epithelial-mesenchymal transition (EMT), metastasis, apoptosis and self-renewal of cancer stem cells.[18] AURKA may play a role in impaired cell viability and enhanced apoptosis in UCEC.[19] Further research found that AURKA inhibitor Alisertib may treat UCEC, revealing that AURKA is a promising therapeutic target.[20] Liu found that AURKA is highly expressed in HCC and predicted 8 AURKA-related genes with prognostic value, and then successfully constructed a gene signature.