Moreover, by generating the BAF53b-GFP;EF1α-GsαR201C reporter mouse model with pan-neuronal GFP expression along with immunolocalization studies, we show that the sensory innervation pattern of mouse Gsα-mutated skeletal compartments and FD lesions does not show morphological abnormalities. The gene discussed is ACTL6B; the disease is Fabry disease.