BRCA1 and Familial prostate cancer: In contrast, a family history of prostate cancer was associated with PV only in BRCA2. Based on the fact that overall BRCA2 is detected at a lower rate than BRCA1 within the current coverage conditions and at a higher rate in other conditions, it is necessary to discuss the addition of a family history of prostate cancer to MICC that will increase the detection rate of BRCA2 [16].