In the ROC analysis performed to evaluate the diagnostic performance of GCF and serum biomarkers in identifying AP abscess formation, the GCF sclerostin test was found to be at the best threshold value (> 54.9 ng/mL), with sensitivity and specificity values of 65.5% and 98.6%, respectively, and an AUC of 0.768 (p < 0.0001). The gene discussed is SOST; the disease is alkaline phosphatase measurement.