Thesepatients predominantly exhibited conjugated hyperbilirubinemia, coupled with elevated liver enzyme levels that warrant attention.Notably, the median AST level reached 460 IU/L (IQR: 207-627), clearly indicating that AST levels were consistently higher than ALT,which had a median of only 102 IU/L (IQR: 86-109.5). The gene discussed is GOT1; the disease is Hyperbilirubinemia.