Correlation analysis further demonstrated that PWR was negatively associated with ALT, total bilirubin, INR, PT, type IV collagen, hyaluronic acid, and portal vein diameter, while it showed positive correlations with albumin, total cholesterol, LDL-C, triglycerides, and laminin in patients with WD (P < 0.05 for all, Table 4). The gene discussed is GPT; the disease is Wilson disease.