A study by Baker et al. examined 38 immune markers among children (EGF, FGF2, CCL11(eotaxin), TGFA, CSF3, CSF2, FLT3LG, VEGFA ,CX3CL1 (fractalkine), CXCL1P1, CCL7, CCL22, CXCL8, CXCL10(IP-10), CCL2, CCL3, CCL4, IFNA2, IFNG, IL-1a, IL-1b, IL-1RN, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IL-10, IL-12p40, IL-12p70, IL-13, IL-15, IL-17, CD40L, TNF, and LTA) finding that ten were elevated due to dental caries [17]. This evidence concerns the gene IL1RN and dental caries.