PDZD8 and hydrops fetalis: The association of these genes with sixteen HF outcomes obtained from the IEU OpenGWAS project was assessed, yielding 202 associations, and twenty of these associations, relating to 6 genes (ADD3, HSPA12A, SLC18A2, PDZD8, DUSP5, CASP7), were statistically significant with P<0.05 (Table 3).