Moreover, the study identified human ACT-susceptibility genes such as ADD3, HSPA12A, SLC18A2, PDZD8, DUSP5, CASP7, GPC6, UGGT2, SLAIN1, POU4F1, MBNL2 that were significantly associated with HF outcomes in humans using MR analysis. The gene discussed is DUSP5; the disease is hydrops fetalis.