Moreover, the study identified human ACT-susceptibility genes such as ADD3, HSPA12A, SLC18A2, PDZD8, DUSP5, CASP7, GPC6, UGGT2, SLAIN1, POU4F1, MBNL2 that were significantly associated with HF outcomes in humans using MR analysis. This evidence concerns the gene UGGT2 and hydrops fetalis.