Inhibiting this overexpressed P-gp is a direct approach to overcoming cancer MDR.42 Xu et al. reported a long-circulating liposome with two chemotherapeutics doxorubicin (Dox) and Schizandrin for liver cancer and reversing MDR with a reversion index of 30.28.43 The liposomal formulation with DSPE-PEG 2000 provided prolonged circulation. This evidence concerns the gene PGP and cancer.