For example, DNAm annotated to the genes SKI, ZNF544, ST3GAL4, and PEX2 in cord blood at birth were prospectively associated with childhood ADHD symptom trajectories (12), and CREB5, ZBTB38, PPIL2, TRERF1, and ERC2 with ADHD childhood symptoms (14). The gene discussed is TRERF1; the disease is attention deficit-hyperactivity disorder.