The common culprits of drug-induced pruritus include immune checkpoint inhibitors;39 agents targeting epidermal growth factor receptor, B-Raf proto-oncogene, cytotoxic T-lymphocyte-associated protein-4, and Programmed cell Death protein-1/Programmed cell Death-Ligand-1 (PD-1/PD-1L).39 This evidence concerns the gene PDCD1 and Pruritus.