The sensitivity analyses with altered criteria for organ failure and infection showed similar AUCs of calprotectin and CRP (AUC 0.59–0.61 for calprotectin and AUC 0.68–0.73 for CRP) to distinguish sepsis from non-sepsis, compared to the operational sepsis criteria used in the main analyses (see Table 4). The gene discussed is CRP; the disease is Sepsis.