CHMP5 and acute lymphoblastic leukemia: More specifically, comparison of CHMP5 expression in pediatric T-ALL samples versus normal thymocytes (GSE33470, GSE33469)54,55 revealed higher CHMP5 transcripts in T-ALL cells (Fig. 5a) which translated to >5-fold more CHMP5 proteins in primary human T-ALL relative to healthy T-cells (Fig. 5b, c).