We detected proteins that were previously identified in HSF2 coimmunoprecipitation experiments in the mouse testis and/or prostate cancer PC-3 cells,45 reinforcing the physiological relevance of our HSF2 coimmunoprecipitation experiment: among them, DNA topoisomerase TOP2A, YWHAE (14-3-3 protein epsilon) and Talin-1 (Table 1), which was validated as a HSF2 partner by orthogonal methods45 and is involved in the development of neurites.46 The gene discussed is TLN1; the disease is Familial prostate cancer.