SLC26A2 and nephrolithiasis: Also, SLC26A2 (expressed at the apical membrane of IECs with higher levels in the colon compared to the small intestine) [59, 60] does not appear to play a significant role in intestinal oxalate transport [61] as mutations in the SLC26A2 gene have not been linked to hyperoxaluria or nephrolithiasis in mice or patients [59].