The 35 studies using a ~ 40 mU/m2/min insulin infusion rate comprised 985 participants (256 Lean, 497 OW and 232 T2D participants) and included 16 cross‐sectional studies, 2 cohort studies, 11 randomised controlled trials (RCTs), and 6 clinical trials. The gene discussed is INS; the disease is type 2 diabetes mellitus.