Zhu and collaborators have demonstrated that lnc‐FAL1, a lncRNA that promotes oxaliplatin chemoresistance in colorectal cancer (CRC), is mainly derived from exosomes secreted by cancer‐associated fibroblasts (CAFs), inhibiting oxaliplatin‐induced autophagy by acting as a scaffold for the interaction between Beclin‐1 and TRIM3 (promoting TRIM3‐dependent Beclin‐1 polyubiquitination and degradation).150. This evidence concerns the gene BECN1 and cancer.