INS and hyperinsulinism: In the six equids with hyperinsulinemia and laminitis, insulin concentration (median, 618 pmol/L; IQR, 545–2153) was not different (p = 0.33) than in the six hyperinsulinemic horses without laminitis (median, 686 pmol/L; IQR, 472–919; Supporting Information File 1).