Similarly, we are the first study to explore passive psychological stress in the context of inflammation and habitual SB volume so although we found no significant relationships, in other populations (such as those with obesity), the circulating IL‐6 reactivity to a passive stressor and SB relationship may be different as associations between SB volume and CVD risk are stronger in those who are physically inactive, hence, psychological stress‐induced circulating IL‐6 responses may also differ in a sample of physically inactive individuals (Katzmarzyk et al. 2019). Here, IL6 is linked to obesity due to melanocortin 4 receptor deficiency.