Their study elucidates that LDRT recruits stem cell-like progenitor exhausted CD8+ T cells (CD8+ Tpex) from draining lymph nodes to the tumor site via the CXCL10/CXCR3 axis, enhancing the sensitivity of tumors to DPVB and achieving tumor regression [201]. This evidence concerns the gene CXCR3 and neoplasm.