While it is typically less severe than severe combined immunodeficiency (SCID), it does share certain clinical features with STAT3 deficiency [25, 26] This further complicates the process of distinguishing HIES from other inborn errors of immunity (IEI).In particular, DOCK8 deficiency is associated with a unique presentation that includes severe cutaneous viral infections such as warts and Molluscum. This evidence concerns the gene DOCK8 and hyperinsulinemic hypoglycemia, familial, 4.